The sex and geometry of inter-organ communication

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• Professor Irene Miguel-Aliaga, The Francis Crick Institute
• Wednesday 01 October 2025, 15:00-16:00
• MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

If you have a question about this talk, please contact Lisa Arnold.

Our research explores the idiosyncrasies of adult organs: how they differ between the sexes and are remodelled by their environment. Our work in Drosophila uncovered a gut-reproductive axis that differs between the sexes and impacts food intake, gamete production and tumour susceptibility. Investigating how the intestine senses and responds to nutrients, we also discovered an intestinal zinc sensor that promotes Tor signalling to sustain food intake and developmental growth. More recently, we have investigated the sex and reproductive plasticity of the mammalian intestine in both mice and humans. We have also become very interested in the idea that the shape and position of the intestine constrain or enable its functions, and we have developed new methods to describe and interrogate these new dimensions to organ function. I will likely present some of this work.

This talk is part of the MRC Mitochondrial Biology Unit Seminars series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• CamBridgeSens
• Cambridge talks
• Life Science Interface Seminars
• MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY
• MRC Mitochondrial Biology Unit Seminars
• Trust & Technology Initiative - interesting events
• yk449

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