University of Cambridge > Talks.cam > MRC LMB Seminar Series > 2024 Milstein Lecture: Centrioles in homeostasis, disease and evolution: tiny organelles, multiple and critical functions - IN PERSON ONLY

2024 Milstein Lecture: Centrioles in homeostasis, disease and evolution: tiny organelles, multiple and critical functions - IN PERSON ONLY

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Centrioles/basal bodies are microtubule-based structures that form centrosomes, a major microtubule organising center, and template the formation of the cilium, which is important for signalling and motility. While these structures were described more than a century ago, due to their small size, only recently tools became available to investigate them in different contexts. I will discuss efforts from our laboratory towards decoding the principles that regulate the assembly and maintenance of these structures, as well as their variations observed at different scales and contexts, in different tissues, in disease and evolution.

This talk is part of the MRC LMB Seminar Series series.

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