Implications and molecular mechanisms of MOK, a new signaling kinase in neurodegenerative neuroinflammation

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• Dr Cintia Roodveldt University of Seville
• Friday 10 November 2023, 12:30-13:30
• Seminar Room (Level 2), Dept of Pharmacology .

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Dr Cintia Roodveldt

University of Seville

Biography

After graduating in Biotechnology (Universidad Nacional del Litoral, Argentina, 1999), Dr Roodveldt completed a PhD (2005, The Weizmann Institute of Science, Israel; Dan S. Tawfik’s lab) in the field of ‘enzyme evolution and emergence of new enzyme functions’. She then undertook a Postdoc at Prof. Chris M. Dobson’s lab (University of Cambridge, 2006-2009), investigating the ‘molecular mechanisms of Hsp70 chaperone system and a-synuclein aggregates linked to Parkinson’s disease’.

In 2009 she joined David Pozo’s lab, a neuroimmunology lab, at CABIMER Center (Seville, Spain) and started a new line of research on the effect of protein aggregates in innate immunity. Since 2012, and having attained competitive tenure track positions (e.g. ‘Ramón y Cajal’ Researcher), they have led a research team studying the ‘mechanisms of microglial neuroinflammation triggered by a-synuclein aggregates and novel immunization strategies in Parkinson’. Her current research lines focus on the ‘identification of new signalling pathways and therapeutic targets related to immune dysregulation in neurodegenerative diseases, particularly ALS and Parkinson’.

Zoom link: https://zoom.us/j/97143593246?pwd=ckVsZFo2ZGlPei8vVGhoWXg1L0w5QT09

Meeting ID: 971 4359 3246

Passcode: LkGiwj915c

This talk is part of the Department of Pharmacology Seminar Series series.

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