University of Cambridge > Talks.cam > Departmental Seminar Programme, Department of Veterinary Medicine > Of men and beasts, parasite-altered transmembrane transport

Of men and beasts, parasite-altered transmembrane transport

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Apicomplexan parasites are an important cause of disease in animals and man but are poorly controlled. Several of these parasites, including Plasmodium and Babesia, reside within the red blood cells of their hosts. During intracellular development the parasites alter the permeability of their host red blood cells. This can contribute to parasite survival by modulating nutrient uptake, waste removal and volume and ion regulation. For these reasons, the transport pathways that underlie this process have been proposed as drug targets and/or selective routes to target the internal parasite. The talk will cover our present understanding of this phenomenon and also cover some recent data derived from Plasmodium-infected liver cells.

This talk is part of the Departmental Seminar Programme, Department of Veterinary Medicine series.

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