CRISPR Cas Genome Editors - from Bacteria to Biotech

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• Prof Martin Jínek (Department of Biochemistry, University of Zürich)
• Thursday 25 February 2021, 18:15-19:45
• Online.

If you have a question about this talk, please contact Miroslava Novoveska.

Link to join the YT live stream:

https://youtu.be/znlX1p3Tubs

The CRISPR -Cas system constitutes a genome defence mechanism that protects bacteria from invasive genetic elements such as viruses. The system functions by using guide RNA molecules in conjunction with programmable nucleases such as Cas9 to recognize and cleave invader DNA . CRISPR-associated nucleases have been repurposed as powerful tools for precision genome editing in eukaryotic cells and organisms. My research aims to elucidate the molecular mechanisms of CRISPR -associated nucleases using a combination of structural, biochemical and biophysical approaches. These studies provide the foundation for understanding the molecular function of CRISPR genome editors and for the ongoing development of CRISPR -based genome editing for biotechnological and therapeutic applications.

This talk is part of the Trinity College Science Society (TCSS) series.

This talk is included in these lists:

• Chris Davis' list
• Guy Emerson's list
• Online
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