Targeting the Tumour Microenvironment
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If you have a question about this talk, please contact Kate Davenport.
The tumour microenvironment is characterised by the infiltration and activation of stromal cells and establishment of both reinforcing tumour-stroma crosstalk pathways and crosstalk between different stromal cell populations. This seminar will focus on the role of the cancer-associated fibroblasts (CAFs) and pericytes in breast cancer progression and the therapeutic strategies we are developing, including CAR T -cells and antibody-drug conjugates, to target these activated stromal cell populations, particularly in the metastatic setting.
This talk is part of the Cancer Research UK Cambridge Institute (CRUK CI) Seminars in Cancer series.
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