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VCAM1, brain ageing, and the 'vampire hypothesis'

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If you have a question about this talk, please contact Veronica Kane Dickson.

This week’s paper discusses the action of a key factor in brain ageing, VCAM1 , discovered to be relevant to what has been called the vampire hypothesis – effects of giving an old mouse young blood.

Please find the paper at

Yousef et al (2019) Nature Medicine. Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1 .

This talk is part of the Dementia Journal Club series.

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