The development of treatments that will help patients with structural damage to the CNS is one of the great remaining unmet needs in medicine. These disorders include Parkinson’s disease, Huntington’s disease, Alzheimer’s disease and dementias, multiple sclerosis, spinal cord injury, traumatic brain injury, and glaucoma. They affect a large proportion of the severely disabled people in Western societies. All these conditions have damage to axons as a common feature. This training meeting is focussed on the problem of axonal damage (axonopathy), which is central to attempts to understand how the central nervous system (CNS) can be damaged, how this damage might be prevented or limited, and how new ways of repairing the CNS might be developed. The study of axonal damage and repair can, and should, be approached in a wide variety of ways, and this is what gives the programme its multi-disciplinary scope, even though it is focussed on a common topic.

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