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Therese Graversen (Københavns Universitet (University of Copenhagen))
Wednesday 09 November 2016, 10:15-11:00
An exact, efficient, and flexible representation of statistical models for DNA profiles
- 👤 Speaker: Therese Graversen (Københavns Universitet (University of Copenhagen))
- 📅 Date & Time: Wednesday 09 November 2016, 10:15 - 11:00
- 📍 Venue: Seminar Room 1, Newton Institute
Abstract
Many different models have been proposed for a statistical interpretation of mixed DNA profiles. Regardless of the model, a computational bottleneck lies in the necessity to handle the large set of possible combinations of DNA profiles for the contributors to the DNA sample.
I will explain how models can be specified in a very general setup that makes it simple to compute both the likelihood and many other quantities that are crucial to a thorough statistical analysis. Notably all computations in this setup are exact, whilst still efficient.
I have used this setup to implement the statistical software package DNAmixtures.
Related Links
- http://dnamixtures.r-forge.r-project.org/ – The DNAmixtures software package
- http://dx.doi.org/10.1007/s11222-014-9451-7 – Computational aspects of DNA mixture analysis (Graversen and Lauritzen 2015)
Series This talk is part of the Isaac Newton Institute Seminar Series series.
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