Structure vs. Function: A quantitative analysis of chromosome architecture

Luca Giorgetti - Friedrich Miescher Institute, Basel.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 14 October 2016, 14:30-15:30

Cambridge Haematopoiesis Seminars: Timm Schroeder & Ellen Rothenberg

Timm Schroeder - ETH Zurich & Ellen Rothenburg - Caltech.

Clifford Allbutt Lecture Theatre, Clifford Allbutt Building (former LMB building).

Thursday 10 March 2016, 17:00-18:00

Single-cell analysis of hematopoietic stem cell identity and behaviour

David Knapp -- Terry Fox Laboratory, Vancouver.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Tuesday 08 March 2016, 10:00-11:00

Placing BETs on hold in AML

Mark Dawson - Peter MacCallum Cancer Centre, Melbourne, Australia.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Wednesday 20 January 2016, 16:30-17:30

Sub-clonal heterogeneity in chronic myeloid leukemia

Mike Schmitt - Fred Hutchinson Cancer Research Centre, University of Washington.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Monday 18 January 2016, 16:00-17:00

Insights into mammalian hematopoiesis from comparative functional genomic

Please note that this seminar is at 11am

Prof. Ross Hardison (Penn State).

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Wednesday 17 June 2015, 11:00-12:00

Making Hematopoietic Stem Cells: Backwards and Sideways

Dr Derrick Rossi (Harvard, USA).

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 05 June 2015, 16:00-17:00

Identification of Regulatory Networks in HSCs and Their Immediate Progeny via Integrated Proteome, Transcriptome, and DNA Methylome Analysis

Dr Nina Cabezas (DKFZ, Heidelberg).

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Wednesday 20 May 2015, 13:00-14:00

Title to be confirmed

Prof. Frederic Geissman, Kings College London.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 08 May 2015, 16:00-17:00

Aberrant chromatin programming in AML

Prof. Constanze Bonifer, University of Birmingham.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 20 March 2015, 16:00-17:00

Predictive Engineering of Cell Fate

Please note that this seminar is at 10am

Prof. Peter Zandstra, University of Toronto.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Wednesday 11 February 2015, 10:00-11:00

Opening up the stem cell niche for human and mouse hematopoietic stem cells

Please note the different location of this seminar

Prof. Claudia Waskow, Center for Regenerative Therapies TU Dresden.

Clifford Allbutt Lecture Theatre, Clifford Allbutt Building (former LMB building).

Thursday 29 January 2015, 16:00-17:00

Mimicking of the process of human erythropoiesis using in vitro culture; studies on red blood cell membrane assembly and also use of 3D scaffolds

Dr Ashley Toye, University of Bristol.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 14 November 2014, 16:00-17:00

Hematopoietic stem cell formation in the embryo

Prof. Nancy Speck, University of Pennsylvania.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Thursday 16 October 2014, 16:00-17:00

Clinical and Biological Impact of Flt3 mutations in Acute Leukaemia

Dr Adam Mead, University of Oxford.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 19 September 2014, 16:00-17:00

Aurora A kinase and RPS14: new players in the myeloproliferative neoplasms

Prof. John Crispino, Northwestern University, Chicago.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Monday 08 September 2014, 16:00-17:00

Targeting survival pathways in CML stem cell persistence and TKI-resistance

Prof. Tessa Holyoake, University of Glasgow.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Monday 14 July 2014, 16:00-17:00

Dnmt3a in Normal and Malignant Hematopoiesis

Please note the different location of this seminar

Prof Margaret Goodell, Stem Cells and Regenerative Medicine Center, Baylor College of Medicine.

Clifford Allbutt Lecture Theatre, Clifford Allbutt Building (former LMB building).

Wednesday 09 July 2014, 13:00-14:00

Normal and leukaemic (AML) human stem/progenitor cells

Prof. Paresh Vyas, WIMM, Oxford University.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Wednesday 02 July 2014, 16:15-17:15

Regulation of Akt by the Sin1-mTOR complex in lymphocytes

Prof. Bing Su (Department of Immunobiology at Yale, and Shanghai Institute of Immunology at Shanghai JiaoTong University School of Medicine).

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 06 June 2014, 16:00-17:00

Familial thrombocytopenias with predisposition to leukemia: RUNX1 targets

Dr Hana Raslova, Institut Gustave Roussy, Paris.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Tuesday 13 May 2014, 16:00-17:00

Engaging mechanisms of negative B cell selection to overcome drug-resistance in leukaemia

Prof. Markus Müschen, UCSF.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Tuesday 22 April 2014, 15:00-16:00

Neuroendocrine regulation of the bone marrow stem-cell niche

Simón Méndez-Ferrer, CNIC, Madrid, Spain.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 04 April 2014, 16:00-17:00

Heterogeneity of hematopoietic stem and progenitor cell populations: implications for ageing and regeneration

Claus Nerlov, University of Oxford.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 21 March 2014, 16:00-17:00

Of mice and men and Tasmanian devils; assembling reference genomes from single cells.

Dr Mark Hills, Terry Fox Lab, Vancouver, Canada.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 14 March 2014, 11:00-12:00

Notch and Wnt Signaling: From Hematopoeitic Stem Cells to Leukemia

Anna Bigas. Cancer and Stem Cells Research Group. Institut Hospital del Mar d'Investigacions Mèdiques (IMIM).

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 07 March 2014, 13:00-14:00

4D tracking of haematopoietic stem and progenitor cells in their bone marrow microenvironment

Dr Cristina Lo Celso, Imperial College London.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 07 February 2014, 16:00-17:00

Mechanistic insight into ALK receptor tyrosine kinase in human cancer biology

Bengt Hallberg (Umea University, Sweden).

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Tuesday 07 January 2014, 16:00-17:00

Cancer Epigenetics: Appreciating the beauty and complexity of a string of pearls

Mark Dawson, University of Cambridge.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 22 November 2013, 16:00-17:00

Haematopoietic Stem Cells

Prof. Connie Eaves, Terry Fox Laboratory, Vancouver.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Tuesday 12 November 2013, 12:30-13:30

Emerging therapeutic strategies for treating the first molecular disease

Prof. James Douglas Engel, University of Michigan Medical School, USA.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 08 November 2013, 16:00-17:00

Bone marrow environment and platelet production

Assoc. Prof. Alessandra Balduini, University of Pavia Italy, and Tufts University USA.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 18 October 2013, 16:00-17:00

Mutations in Epigenetic Modifiers in Myeloid Malignancies

Dr Ross Levine, Memorial Sloan-Kettering Cancer Center, New York.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Tuesday 15 October 2013, 16:00-17:00

Forward genetic screening using patient CML cells identifies IKAROS as a myeloid tumour suppressor

Dr Philip Beer, Terry Fox Laboratory, Vancouver.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Monday 07 October 2013, 17:00-18:00

Molecular and cellular basis of disease initiation in myeloproliferative neoplasms

Prof. Radek Skoda, Head of the Department of Biomedicine, University Hospital, Basel.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 20 September 2013, 16:00-17:00

Look Beyond the Target: How Lessons from Chronic Myeloid Leukaemia Can Improve Cancer Targeted Therapies

Assoc. Prof. Sin Tiong Ong, Duke-NUS Graduate Medical School Singapore & Duke University Medical Center.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Wednesday 18 September 2013, 11:00-12:00

Polycomb-mediated selfrenewal of young (and aged?) hematopoietic stem cells

Gerald de Haan, Scientific Co-Director, European Research Institute for the Biology of Ageing.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 03 May 2013, 11:00-12:00

Epigenetic reprogramming in mammalian development

Wolf Reik.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 30 November 2012, 16:00-17:00

The Aging of Hematopoietic Stem Cells

David Bryder, Lund University.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Tuesday 30 October 2012, 13:00-14:00

Genome-wide mapping of DNA rearrangements in single cells using DNA template strand sequencing

Peter Lansdorp, European Research Institute on the Biology of Ageing, University of Groningen.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 19 October 2012, 16:00-17:00

Tet proteins and methylcytosine oxidation

Anjana Rao, La Jolla Institute for Allergy and Immunology.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Monday 15 October 2012, 16:00-17:00

Immune cell transdifferentiation

Thomas Graf, Centre for Genomic Regulation (Barcelona).

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 11 May 2012, 16:00-17:00

Local interactions and genome-wide co-associations of proto-oncogenes: the short and the long of it.

Cameron Osborne, Babraham Institute.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 23 March 2012, 16:00-17:00

How do enhancers and promoters interact and what are the consequences ?

Doug Higgs, Weatherall Institute, Oxford,.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 27 January 2012, 16:00-17:00

Commitment and plasticity in the B cell lineage

Research Institute of Molecular Pathology Vienna, Austria.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Tuesday 06 December 2011, 16:00-17:00

Long non-coding and extracoding RNAs in normal haematopoiesis and leukemia

Dan Tenen, Cancer Science Institute of Singapore and Harvard Medical School.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Monday 07 November 2011, 16:00-17:00

Chromatin, chromosome and nuclear dynamics, links to genome function

Peter Fraser, Babraham Institute.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 23 September 2011, 16:00-17:00

Genome-wide DNA methylation analysis in stem cells and cancer

Christoph Bock, Broad Institute.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 16 September 2011, 16:00-17:00

Development of hematopoietic stem cells: an outline of the final scenario

Shin-Ichi Nishikawa, Riken CDB, Kobe.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Wednesday 06 July 2011, 10:00-11:00

Why do we need a Fanconi Anaemia DNA repair pathway?

KJ Patel, MRC LMB, Cambridge.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 17 June 2011, 16:00-17:00

Genetics and therapy of AML: role of mutations in the epigenetic machinery

Ross Levine, Memorial Sloan-Kettering, New York.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Thursday 09 June 2011, 13:30-14:30

The development of HSCs: endothelial to hematopoietic transition

Elaine Dzierzak, Erasmus MC, Rotterdam.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 13 May 2011, 16:00-17:00

Studying precancerous stem cells in mouse models of T cell leukaemia

Matthew McCormack, WEHI, Melbourne.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Monday 18 April 2011, 10:30-11:30

Genetic complexity in MPN and MDS/MPN

Nick Cross, Univeristy of Southampton.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 25 February 2011, 16:00-17:00

Insights into the molecular basis of myelodysplastic syndrome

Ben Ebert, Department of Medicine, Harvard Medical School.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Thursday 11 November 2010, 15:00-16:00

Leukemic stem cells - a challenging adversary

Keith Humphries, Terry Fox Laboratories, Vancouver, Canada.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 15 October 2010, 16:00-17:00

Initiation and progression of leukemia – lessons from Down Syndrome

Shai Izraeli, Tel Aviv University, Israel.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Thursday 09 September 2010, 16:00-17:00

Modeling APL pathogenesis through therapy response

Hugues de Thé MD, PhD, University of Paris, Head, INSERM/CNRS/University Paris 7.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Thursday 29 July 2010, 13:00-14:00

Interactions between a cell signalling pathway and a haematopoietic transcriptional network

John Pimanda, University of New South Wales.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 11 June 2010, 16:00-17:00

In vivo imaging of haematopoietic stem and progenitor cells interacting with their niche(s)

Cristina Lo Celso, Imperial College, London.

Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

Friday 04 June 2010, 16:00-17:00