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CRISPR Genome editing: Design & Strategy

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If you have a question about this talk, please contact Dr Barry Rosen AstraZeneca; Dr Mark Thomas Wellcome Trust Sanger Institute; Dr Emmanouil Metzakopian Wellcome Trust Sanger Institute.

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2-Day Intensive “CRISPR Genome editing: Design & Strategy” Course 22-23 June 2017

Homerton College, Cambridge

The targeted addition of genes to mammalian genomes is fundamental practice in biotechnology, basic life science research and for gene therapy in the clinics. The majority of methods for the stable insertion of genes into cells rely on random genomic transgene integration followed by laborious antibiotic selection and screening steps. This unwieldy random integration can lead to several confounding effects on gene expression, including multiple integrations per cell, the disruption of endogenous genes at or near the site of integration, and unstable transgene expression due to epigenetic regulation. These limitations often lead to unpredictable cell behaviour, irreproducible results and increase the chance of erroneous data interpretation.

The clustered regularly interspaced palindromic repeats or ‘CRISPR’ as they are more widely known overcome almost all of these concerns,

as this technology facilitates the precise addition of transgenes to specific locations in mammalian genomes.

On this CamBioScience ‘Genome Editing: CRISPR Design & Strategy’ Course you will learn how to best implement techniques relating to this versatile and programmable sequence-specific endonuclease to expedite and enhance your research or product development.

All CamBioScience courses are specifically designed to perfectly match the expectations of our participants. Our world leading instructors provide the Cambridge expertise for you to advance your individual research! Click here for impressions of our last ‘Genome Editing’ course.

IMPORTANT : Don’t forget to bring your laptop for the bioinformatics training.


This talk is part of the CRISPR Genome Editing Courses series.

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