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Large-scale brain networks in cognition: A unifying triple network model

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An understanding of how the brain produces cognition ultimately depends on knowledge of its large-scale organization and wiring. Despite recent progress in understanding large-scale brain connectivity, mapping their relation to cognition remains a significant challenge. In this talk, I describe these challenges and discuss recent advances in disentangling the role of core brain networks in cognition. A unifying triple network model of salience and network switching is proposed and its role in attention and cognitive control will be examined. I then examine the development of core neurocognitive brain networks and discuss how the triple network model can help synthesize extant findings of aberrant brain connectivity into a unified framework for understanding key features of several major psychopathologies.

This talk is part of the Brain Mapping Unit Networks Meeting and the Cambridge Connectome Consortium series.

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