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University of Cambridge > Talks.cam > Sainsbury Laboratory Seminars > Single-Cell and Spatial Dissection of Plant-Microbe Interactions
Single-Cell and Spatial Dissection of Plant-Microbe InteractionsAdd to your list(s) Download to your calendar using vCal
If you have a question about this talk, please contact Sainsbury Laboratory. In multicellular organisms, individual cells interpret a multitude of developmental and environmental signals through unique gene regulatory mechanisms, leading to highly diverse cellular responses. A comprehensive understanding of tissue function necessitates investigating these complex and heterogeneous gene regulatory patterns, all while maintaining the native three-dimensional (3D) tissue context. In this seminar, I will cover two main topics: (1) the use of single-cell multiomics and spatial transcriptomics in studying spatiotemporal dynamics of gene regulatory mechanisms at the single-cell resolution in the model plant Arabidopsis thaliana, and (2) the development of PHYTO Map, a novel method for multiplexed single-cell 3D spatial gene expression analysis in whole-mount plant tissue. I will present how these methodologies allow for unprecedented resolution in studying interactions between plants and microbes. This talk is part of the Sainsbury Laboratory Seminars series. This talk is included in these lists:
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