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Notch and peripheral immunity

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If you have a question about this talk, please contact Prof. Jim Kaufman.

Host: Chris Rudd (cer51@hermes.cam.ac.uk)

Research Interests: An ability to generate immune responses to invading pathogens is vital to our well being and survival yet over-vigorous or inappropriate responses can lead to debilitating or life threatening conditions such as autoimmunity (e.g. diabetes, rheumatoid arthritis) and allergy. Further, as our understanding of disease develops we find that dysregulated inflammatory responses are associated with conditions as diverse as Alzheimer’s disease and obesity. An understanding of and an ability to control inappropriate immunity and inflammation lie therefore on the path to successful treatment of these varied diseases. Maggie’s own work uses a range of organisms from zebrafish to humans to study at the molecular, cellular and whole individual level not only the basis for disease but also potential approaches to therapy.

This talk is part of the Immunology in Pathology series.

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