The Timescale Dynamics of Epilepsies: From Seconds to Decades

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• Christophe Bernard, Institute of Systems Neuroscience, Inserm, France
• Thursday 31 March 2022, 11:00-12:00
• Electrical Engineering, Department of Engineering - CGC Seminar Room, 9 JJ Thomson Avenue, Cambridge, CB3 0FA.

If you have a question about this talk, please contact Kirsty Shepherd.

Continuous long-term recordings (months to years) in patients with epilepsy directly show that seizures are regulated in a circadian manner in 80% of the cases. Besides, these recordings allowed to prove the presence of a much slower rhythm (days to weeks) of seizures. They strongly suggest the existence of specific molecular processes that influence the time of occurrence of seizures. I will show that cortical structures undergo dynamic reconfiguration of their molecular architecture in a daily manner in health and disease. Accounting for daily and multidien molecular rhythms is essential to our understanding of brain function and dysfunction.

This talk is part of the Electrical Engineering series.

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• Electrical Engineering
• Electrical Engineering, Department of Engineering - CGC Seminar Room, 9 JJ Thomson Avenue, Cambridge, CB3 0FA

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