Taking control of innate immunity with nanobiologics

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• Willem Mulder, Icahn School of Medicine at Mount Sinai, New York
• Thursday 05 November 2020, 12:30-13:30
• Zoom Webinar ask for details vr314@medschl.cam.ac.uk.

If you have a question about this talk, please contact vr314.

Immunotherapy is revolutionizing the treatment of diseases. Most of the immunotherapy strategies currently being developed engage the adaptive immune system. In recent years, emerging evidence has shown that the innate immune system displays long-term changes in its functional program through metabolic and epigenetic programming of myeloid cells (monocytes, macrophages, dendritic cells). Therefore, targeting myeloid cells and their progenitors is a powerful ‘therapeutic framework’ to regulate the delicate balance of immune homeostasis, priming/training and tolerance. This Presentation will showcase how nanobiologic-based immunotherapies can be applied to achieve long-term therapeutic benefits in detrimental diseases, including cancer and cardiovascular diseases as well as to prevent organ rejection after transplantation. In addition, a translational workflow involving innovative multimodality imaging approaches and large animal models will be discussed.

This talk is part of the Cambridge Cardiovascular Seminar Series series.

This talk is included in these lists:

• Cambridge Cardiovascular Seminar Series
• Cardiovascular Epidemiology Unit Special Seminars
• Zoom Webinar ask for details vr314@medschl.cam.ac.uk
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