University of Cambridge > Talks.cam > Keyser Group Seminar > Theory of Driven Polymer Translocation through Nanopores

Theory of Driven Polymer Translocation through Nanopores

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The translocation dynamics of polymers though nanopores driven by external fields is a far-from-equilibrium process, which can be understood based on the tension propagation (TP) theory of Sakaue [1]. In particular, the coarse grained Brownian Dynamics TP theory within the iso-flux (IFTP) assumption [2] allows a self-consistent derivation of analytic equations of motion for the dynamics, including an explicit form for the chain length dependence of the average translocation time [3]. In this talk I will discuss the fundamentals of the IFTP theory and its various applications theory to translocation dynamics of long semi-flexible [4] and end-pulled polymer chains [5]. Time permitting I will also discuss recent works trying to elucidate the role of hydrodynamics and electrostatic interactions on translocation of rod-like molecules in finite and infinite cylindrical nanopores [6].

1. T. Sakaue, Phys. Rev. E 76 , 021803 (2007). 2. P. Rowghanian and A. Y. Grosberg, J. Phys. Chem. B 115 , 14127 (2011). 3. J. Sarabadani, T. Ikonen and T. Ala-Nissila, J. Chem. Phys. 141, 214907 (2014); J. Sarabadani and T. Ala-Nissila, J. Phys. Cond. Matt. 30, 274002 (2018). 4. J. Sarabadani, Timo Ikonen, Harri Mökkönen, Tapio Ala-Nissila, Spencer Carson, and Meni Wanunu, Sci. Reps. 7, 7423 (2017). 5. J. Sarabadani, B. Ghosh, S. Chaudhury, and T. Ala-Nissila, EPL 120 , 38004 (2017). 6. S. Buyukdagli and T. Ala-Nissila, J. Chem. Phys. 147, 114904 (2017); J. Chem. Phys. 147, 144901 (2017); S. Buyukdagli, R. Blossey, and T. Ala-Nissila, Phys. Rev. Lett. 114, 088303 (2015).

This talk is part of the Keyser Group Seminar series.

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