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CATEGORIES:Adrian Seminars in Neuroscience
SUMMARY:TODAY Adrian Seminar - &quot\;Functional synaptic 
 architecture of visual cortex&quot\; - David Fitzp
 atrick\, Research Group Leader &amp\; Scientific D
 irector\, Max Planck Florida Institute for Neurosc
 ience
DTSTART;TZID=Europe/London:20180226T163000
DTEND;TZID=Europe/London:20180226T180000
UID:TALK99184AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/99184
DESCRIPTION:The pioneering work of Hubel and Wiesel defined th
 e fundamental challenge in understanding the funct
 ional organization of visual cortex: How do cortic
 al circuits transform the information supplied by 
 different populations of retinal ganglion cells in
 to coherent representations of the visual world? T
 heir demonstration of emergent properties of corti
 cal circuits such as selectivity for the orientati
 on of edges\, and an orderly columnar architecture
  for orientation preference set the stage for a ho
 st of studies that have addressed the circuit mech
 anisms responsible for this transform. While progr
 ess has been substantial\, the fine scale function
 al synaptic architecture that allows individual ne
 urons to integrate inputs from diverse sources to 
 produce coherent sensory representations remains l
 argely unknown. This presentation will focus on re
 cent studies employing a combination of in vivo im
 aging and stimulation techniques with cellular and
  synaptic resolution that provide new insights int
 o the role that functional specificity in synaptic
  connections and dendritic topology play in shapin
 g the cortical transform.
LOCATION:The Hodgkin Huxley Seminar Room\, Department of Ph
 ysiology Development and Neuroscience
CONTACT:Lyn Dakin
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