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CATEGORIES:Isaac Newton Institute Seminar Series
SUMMARY:3D normal coordinate systems for the cortex: appli
cations in the deafened cortices in babies\, adult
s and cats - Tilak Ratnanather (Johns Hopkins Univ
ersity)
DTSTART;TZID=Europe/London:20171117T113000
DTEND;TZID=Europe/London:20171117T121500
UID:TALK95206AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/95206
DESCRIPTION:We describe a surface-based diffeomorphic algorith
m to generate 3D coordinate grids in the cortical
ribbon. In the grid\, normal coordinate lines from
the grey/white (inner) surface to the grey/csf (o
uter) surface are constrained to be normal at the
surfaces. Specifically\, the cortical ribbon is de
scribed by two triangulated surfaces with open bou
ndaries. Conceptually\, the inner surface sits on
top of the white matter structure and the outer on
top of the gray matter. It is assumed that the co
rtical ribbon consists of cortical columns which a
re orthogonal to the white matter surface. This mi
ght be viewed as a consequence of the development
of the columns in the embryo. It is also assumed t
hat the columns are orthogonal to the outer surfac
e. So if we construct a vector field such that the
inner surface evolves diffeomorphically towards t
he outer one\, the distance of the resultant traje
ctories will be a measure of thickness. Applicatio
ns will be described for the deafened auditory cor
tices in babies\, adults and cats. The approach of
fers potential for quantitative functional and his
tological analysis of cortical activity and anatom
y.
(Joint work with Laurent Younes\
, Sylvain Arguillè\;re\, Kwame Kutten\, Andr
ej Kral\, Peter Hubka and Michael Miller). \;<
/span>
LOCATION:Seminar Room 1\, Newton Institute
CONTACT:INI IT
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