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CATEGORIES:Cancer Research UK Cambridge Institute (CRUK CI) S
 eminars in Cancer
SUMMARY:Functional Genomics to Study Cancer - David Sabati
 ni\, Whitehead Institute
DTSTART;TZID=Europe/London:20180628T130000
DTEND;TZID=Europe/London:20180628T140000
UID:TALK87991AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/87991
DESCRIPTION:We are using genome-scale CRISPR-Cas9 genetic scre
 ens in a large number of human cancer cell lines t
 o study cancer. With this approach we are defining
  oncogenic drivers\, synthetic lethal interactions
 \, and genes that modulate the response to drug th
 erapies. I will discuss the big picture lessons we
  have learned as well as the challenges we have en
 countered. I will also present efforts to develop 
 tissue culture media that better mimics the metabo
 lic composition of human plasma and our efforts to
  understand how the metabolic milieu affects the g
 enetic dependencies of cancer cells.\n\n
LOCATION:CRUK CI Lecture Theatre
CONTACT:Kate Davenport
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