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CATEGORIES:Pathology Valedictory Seminars
SUMMARY:Julia Muenzener: Viral subversion of host cell mem
 brane trafficking - Julia Muenzner\, Department of
  Pathology
DTSTART;TZID=Europe/London:20170717T130000
DTEND;TZID=Europe/London:20170717T140000
UID:TALK73521AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/73521
DESCRIPTION:Enveloped viruses acquire their membrane coat from
  host cells and rely on cellular machinery to faci
 litate envelopment and egress of virus progeny. Du
 ring my PhD\, I examined egress-related interactio
 ns between host cell factors and proteins of two v
 iruses\, hepatitis D virus (HDV) and herpes simple
 x virus 1 (HSV-1). Using structural and biochemica
 l techniques\, I investigated the interaction betw
 een the large antigen of HDV and the trafficking p
 rotein clathrin. Only few interactions between HSV
 -1 and cellular proteins promoting  viral egress a
 re known. Using unbiased screening\, I identified 
 novel binding partners of the HSV-1 protein UL56.\
 n
LOCATION:Lecture Theatre\, Department of Pathology\, Tennis
  Court Road
CONTACT:Charlotte Askew
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