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SUMMARY:Resilience vs Vulnerability to Compulsion: behavioral\, neurochemi
 cal and psychopharmacological evidences in rats selected by Schedule-induc
 ed polidipsia - Dr Margarita Moreno\, Tenured Lecturer\, Psychology Depart
 ment\, University of Almería\, Spain
DTSTART:20170712T120000Z
DTEND:20170712T130000Z
UID:TALK73268@talks.cam.ac.uk
CONTACT:Lorraine Coulson
DESCRIPTION:Compulsive behaviour is present in different psychiatric disor
 ders such as OCD\, schizophrenia and drug abuse. In our laboratory we inve
 stigate a compulsive phenotype of rats\, selected by Schedule-Induced Poly
 dipsia (SIP).This procedure\, characterized by the development of nonregul
 atory excessive drinking under intermittent food reinforcement schedules\,
  has been previously proposed as a successful model for obsessive–compul
 sive disorder (OCD)\, schizophrenia\, and alcohol abuse. The lecture revie
 w our main findings in High compulsive drinker rats (HD) versus Low drinke
 r rats (LD) on SIP\; through  the assessment of individual differences in 
 other behaviours related to compulsive spectrum disorders\, psychopharmaco
 logy\, brain neurochemistry and receptors. These studies contribute to elu
 cidate the mechanisms underlying the vulnerability to compulsion \, improv
 ing our knowledge of possible new markers and insights for potential treat
 ments on compulsive behaviours in neuropsychiatric populations.
LOCATION:Ground Floor Lecture Theatre\, Department of Psychology\, Downing
  Site\, Cambridge
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