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SUMMARY:Inference for complex DNA profiles - David Balding (University of 
 Melbourne\; University College London)
DTSTART:20161111T120000Z
DTEND:20161111T123000Z
UID:TALK68945@talks.cam.ac.uk
CONTACT:INI IT
DESCRIPTION:I will outline some interesting aspects of the analysis of com
 plex DNA profiles that have arisen from my recent work in court cases and 
 in my research.&nbsp\; The latter has been largely performed in associatio
 n with former PhD student Christ Steele at UCL and Cellmark UK.&nbsp\; We 
 developed a new statistical model and software for the evaluation of compl
 ex DNA profiles [1]\, and some new approaches to validation.&nbsp\; We als
 o investigated using a dropin model to account for multiple very-low-level
  contributors\, the statistical efficiency of a split-and-replicate profil
 ing strategy versus a one-shot profile\, and a simple linkage adjustment.&
 nbsp\; If time and opportunity permit I will use my last-speaker slot to c
 omment on relevant issues raised during the conference\,<br><ol><li>Steele
  C\, Greenhalgh M\, Balding D  			(2016). 			 Evaluation of low-template D
 NA profiles using peak heights. <i>Statistical Applications in Genetics an
 d Molecular Biology</i>\, 15(5)\, pp. 431-445. 		 doi:10.1515/sagmb-2016-0
 038 						</li></ol> 				 			 		 	 <br><br>
LOCATION:Seminar Room 1\, Newton Institute
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