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SUMMARY:Exploitation of nanoscale particles for DNA analysis and detection
  - Dr. Tracy Melvin (University of Southampton\, UK)
DTSTART:20061127T141500Z
DTEND:20061127T151500Z
UID:TALK5980@talks.cam.ac.uk
CONTACT:K DAS GUPTA
DESCRIPTION:The idea of merging biological and non-biological systems is n
 ot new -\nin fact the long established field of bioconjugate chemistry is 
 based\nupon the covalent attachment of biomolecules and non-biologically\n
 derived molecular species. The self-assembly of these bioconjugates\nprovi
 des a robust approach for the highly sensitive detection of low\ncopy numb
 ers of biomolecules\, an example of such an assay are ELISA\nmethods. Util
 isation of nanobiocongugates for bioanalytical applications\nshould be adv
 antageous for biosensing applications where a physical\nproperty of the na
 nomaterial is exploited to provide an enhanced\ndetection capability. Our 
 main motivation is to create new bioanalytical\ntools integrated within ph
 otonic and MEMS platforms. These technologies\nare being developed for bio
 assays not currently possible by using other\napproaches and include metho
 ds for the analysis of long DNA fragments in\nlow copy number\; in the dev
 elopment of these approaches we have provided\nnew self-assembly nanobioma
 terial fabrication methods. These will be\ndiscussed in the context or our
  overall aims.\n
LOCATION:Mott Seminar Room\, Cavendish Laboratory\, Department of Physics
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