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SUMMARY:Investigating the O3-induced Ca2+ signalling pathway in Arabidopsi
 s - Katie Wilkins (Davies Lab)
DTSTART:20150312T130000Z
DTEND:20150312T133000Z
UID:TALK56595@talks.cam.ac.uk
CONTACT:Stephanie Swarbreck
DESCRIPTION:Ground level ozone is deleterious to both vegetative and repro
 ductive growth with severity depending on the sensitivity of the genotype.
  With the frequency of ozone “episodes” set to increase\, global yield
  losses in 2030 are predicted to be from 4-26% for wheat\, 9.5-19% for soy
 bean\, 2.5-8% for maize and worth up to US$35 billion. Ground level O3 ent
 ers through stomata where it reacts in the apoplast to form several types 
 of Reactive Oxygen Species (ROS) including hydrogen peroxide and hydroxyl 
 radicals. The formation of these ROS plays a significant role in triggerin
 g downstream signalling pathways\, including an increase in [Ca2+]cyt\, RO
 S burst\, alterations in gene transcription and cell death. We have shown 
 that Arabidopsis Annexin1 (AtANN1)\, which is part of a multigene and mult
 ifunction family\, forms a plasma membrane hyperpolarisation-activated Ca2
 + permeable conductance that is activated by hydroxyl radicals (OH▪).  A
 tann1 mutants lack this Ca2+ conductance in both epidermal and root hair a
 pical plasma membrane and are impaired in both H2O2 and salt stress induce
 d Ca2+ signalling. In turn this lack of Ca2+ response has a significant ef
 fect on downstream gene expression. I will present data exploring the role
  of AtANN1 in O3-mediated stress responses\, with a focus on O3-mediated C
 a2+ signatures. Interestingly\, similarities between O3-induced signalling
  and the Hypersensitive Response (HR) are striking\, and preliminary data 
 suggested ANN1 could also play a role in Pathogen-Associated Molecular Pat
 terns (PAMP)-triggered signalling pathways. 
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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