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SUMMARY:Genetic analysis of a somatically acquired trait: immunological se
 lf-tolerance  - Professor Chris Goodnow FRS\, Head of the Dept of Immunolo
 gy at the Australian National University’s John Curtin School of Medical
  Research
DTSTART:20120904T160000Z
DTEND:20120904T170000Z
UID:TALK39585@talks.cam.ac.uk
CONTACT:Dr Tennie Videler
DESCRIPTION:Goodnow “has pioneered in the field of immunology to reveal 
 key mechanisms regulating the immune system\, in particular the ability of
  the immune system to learn to differentiate between our own “self” ti
 ssues and invading foreign microbes. He has also revealed the capacity of 
 the immune system to lay down specific memory of both self and foreign\, s
 o that autoimmunity is minimised while immunity to infection becomes stron
 g”.  \n\nIn this lecture he will present unpublished work analysing the 
 acquisition of self-nonself discrimination by antibodies during germinal c
 enter reactions\, and the impact of inherited and somatically acquired mut
 ations in genes that are critical for B and T cell tolerance.\n
LOCATION:NIHR Cambridge Biomedical Research Centre Lecture theatre\, Robin
 son way
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