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SUMMARY:Locating knots and slipknots in open and closed macromolecules - M
 illett\, K (University of California\, Santa Barbara\, USA)
DTSTART:20120904T152000Z
DTEND:20120904T160000Z
UID:TALK39515@talks.cam.ac.uk
CONTACT:Mustapha Amrani
DESCRIPTION:Once it was imagined that proteins could be knotted\, it was n
 ecessary to find procedures to identify the presence and precise location 
 of knots and\, later\, slipknots in both open and closed macromolecules. W
 hile some of the initially proposed strategies were largely effective they
  often depended upon choices that gave rise to problems. In addition to a 
 review of the historical development of these methods\, we will review met
 hods developed in collaboration with Akos Dobay\, Andrzej Stasiak\, Ben Sh
 eldon and\, later\, with Rawdon in connection with work with Joanna Sułko
 wska and Jose Onuchic on protein structures. The relationship of this appr
 oach with that of other contemporay researcher will be described.\n
LOCATION:Seminar Room 1\, Newton Institute
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