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SUMMARY:Hybrid networks in tomato - Vera Pancaldi\, Gene Silencing
DTSTART:20120210T130000Z
DTEND:20120210T133000Z
UID:TALK35543@talks.cam.ac.uk
CONTACT:24938
DESCRIPTION:This talk will discuss a network approach to investigate hybri
 d vigour and transgressive phenotypes in the hybrids derived from two toma
 to species.\n\nA hybrid displays vigour when its phenotype is different fr
 om the mid-parental value or even outside the range of the parents. In our
  studies and those of others\, extreme transgressive phenotypes were recor
 ded in the second generation hybrids and introgression lines originating f
 rom the two species. A better understanding and prediction of these phenom
 ena could bring considerable improvements to crop production\, increasing 
 plant resistance and yield.\n\nNext-generation sequencing of tomato hybrid
 s allowed us to study the role of small (s)RNAs. After defining the genomi
 c loci at which sRNA production differs between parents and hybrids\, thei
 r overlap with annotated genomic features was analysed. Algorithms for the
  prediction of sRNA targets were used to connect genomic loci and tomato g
 enes\, highlighting that stress response\, resistance and metabolism genes
  might be targeted preferentially. Finally\, this network of sRNAs and gen
 es was combined with a network of co-expressed genes in tomato\, allowing 
 us to further characterise sub-modules of the tomato interactome which are
  affected in the hybridization process.
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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