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SUMMARY:The Roles of Immunity in Influenza Virus Evolution. - John Skehel\
 , NIMR
DTSTART:20120314T190000Z
DTEND:20120314T203000Z
UID:TALK35524@talks.cam.ac.uk
CONTACT:20329
DESCRIPTION:Yearly vaccination against Influenza is necessary because anti
 genic virus variants are selected during infections of partially immune in
 dividuals. Antibodies important in the process of selection recognize viru
 s proteins\, haemagglutinins\, that function in binding and delivering the
  virus to human cells\, during the first stages of virus infection.\nThe m
 ajority of such antibodies block cell binding and most viral variations in
  haemagglutinin\, are in the vicinity of this binding site. Recently\, how
 ever\, antibodies have been described that appear not to select variants b
 ut to react with all influenza viruses. \nCould these antibodies be stock-
 piled in an antiviral drug arsenal for use against the next epidemic? Coul
 d they be induced by a novel single-shot vaccine?\n
LOCATION:Pharmacology Lecture Theatre\, Department of Pharmacology\, Tenni
 s Court Road
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