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SUMMARY:Local Translation at the Synapse - Erin Schuman\, Max Planck Insti
 tute
DTSTART:20120430T151500Z
DTEND:20120430T170000Z
UID:TALK31585@talks.cam.ac.uk
CONTACT:Scientific Meetings Co-ordinator
DESCRIPTION:An individual neuron in the brain possesses approximately 10\,
 000 synapses\, many of which are hundreds of microns away from the cell bo
 dy\, which can process independent streams of information.  During synapti
 c transmission and plasticity\, remodeling of the local proteome occurs vi
 a the regulated synthesis and degradation of new proteins. I will discuss 
 previous and current studies aimed at understanding how local protein synt
 hesis contributes to synaptic function and plasticity.  Using deep-sequenc
 ing techniques and bioinformatic approaches\, we can now describe the loca
 l transcriptome- a large population of previously undetected mRNAs that co
 de for synaptically relevant proteins.
LOCATION:Max Perutz Lecture Theatre\, Medical Research Council (MRC) (MRC 
 Laboratory of Molecular Biol
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