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SUMMARY:RNA Based Mechanism in genetic and epigenetic regulation - Bruno S
 antos
DTSTART:20110526T150000Z
DTEND:20110526T153000Z
UID:TALK30688@talks.cam.ac.uk
CONTACT:Suzy Stoodley
DESCRIPTION:Small (s)RNAs are specificity determinants of silencing mechan
 isms that can target exogenous or endogenous RNA through base pairing to a
 ffect RNA stability and/or translation in a wide spectrum of organisms.  
 In plants there is a particularly complex set of sRNAs and multiple pathwa
 ys of RNA silencing that mediate gene expression and chromatin responses t
 o external stimuli\, differences between genotypes and changes during deve
 lopment. In this project I aim to test the hypothesis that small RNA (sRNA
 ) molecules play a fundamental role in gene regulatory networks (GRNs) in 
 addition to proteins and metabolites.  In this seminar I will present the
  progress made so far on the identification of these networks and the futu
 re plans to model them\, test their topology and make testable predictions
  about their properties and effects on growth and development of plants.
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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