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SUMMARY:Efficient fMRI design for activations and patterns - Rik Henson\, 
 MRC CBU\, Cambridge\, UK.
DTSTART:20260202T123000Z
DTEND:20260202T133000Z
UID:TALK242491@talks.cam.ac.uk
CONTACT:Dace Apšvalka
DESCRIPTION:*Speaker:* Rik Henson\, MRC CBU\, Cambridge\, UK.\n\n*Title:* 
 Efficient fMRI design for activations and patterns.\n\n*Abstract:* How to 
 design an efficient fMRI experiment for activation analysis\, beta-series 
 regression (BSR) and multi-voxel pattern analysis (MVPA).\n\nI will run th
 rough a Matlab livescript (ie interactive notebook) that demonstrates the 
 basic ideas behind statistical power (efficiency) for (within-subject) fMR
 I analyses. The first part reprises what is already available here: https:
 //imaging.mrc-cbu.cam.ac.uk/imaging/DesignEfficiency\, ie explains how to 
 optimise the time between trials (or components of trials) and the orderin
 g of those trials (eg randomised/pseudorandomised/blocked) in order to det
 ect a particular hypothesis (contrast) regarding activation differences be
 tween trial-types in a single voxel/ROI. This will be explained from the p
 erspectives of signal processing\, mathematics and correlations (whichever
  you find more intuitive). The second part explains how optimal estimation
  of activation for single-trials (using LSA\, regularised LSA or LSS\, eg 
 for BSR) depends on the ratio of trial variability to scan noise\, and any
  temporal structure in your trial order. The final part explains how optim
 al estimation of patterns of activity over voxels (for MVPA) also depends 
 on the spatial covariance of trial variability and scan noise.\n\n\n*Venue
 :* MRC CBU West Wing Seminar Room and Zoom https://us02web.zoom.us/j/82385
 113580?pwd=RmxIUmphQW9Ud1JBby9nTDQzR0NRdz09 (Meeting ID: 823 8511 3580\; P
 asscode: 299077)
LOCATION: MRC-CBU\, 15 Chaucer Road\, Cambridge
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