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SUMMARY:Pharmacology Seminar Series: Professor Gopal Sapkota\, Induced-pro
 ximity approaches for targeted protein degradation and dephosphorylation -
  Professor Gopal Sapkota
DTSTART:20260327T130000Z
DTEND:20260327T140000Z
UID:TALK242122@talks.cam.ac.uk
CONTACT:116482
DESCRIPTION:Friday 27 March\, 13:00 - 14:00\n\nSpeaker: Professor Gopal Sa
 pkota\n\nTalk Title: Induced-proximity approaches for targeted protein deg
 radation and dephosphorylation\n\nBiography: The past research in my lab h
 as identified some key molecules in the regulation of the TGFβ/BMP pathwa
 ys and opened up hugely promising avenues for further research on understa
 nding their precise modes of action. My current and future research aims t
 o build on the most exciting discoveries that my group has made and bolste
 r the molecular understanding of their function\, regulation and significa
 nce to human diseases\, particularly cancer. Much of the work involves und
 erstanding their role and regulation through phosphorylation and ubiquityl
 ation processes. I hope the findings will provide a framework of understan
 ding and potential targets that could be exploited for therapeutic interve
 ntion against diseases such as cancer.The past research in my lab has iden
 tified some key molecules in the regulation of the TGFβ/BMP pathways and 
 opened up hugely promising avenues for further research on understanding t
 heir precise modes of action. My current and future research aims to build
  on the most exciting discoveries that my group has made and bolster the m
 olecular understanding of their function\, regulation and significance to 
 human diseases\, particularly cancer. Much of the work involves understand
 ing their role and regulation through phosphorylation and ubiquitylation p
 rocesses. I hope the findings will provide a framework of understanding an
 d potential targets that could be exploited for therapeutic intervention a
 gainst diseases such as cancer.
LOCATION:Seminar Room (Level 2)\, Dept of Pharmacology 
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