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SUMMARY:Pharmacology Seminar Series: Postdoctoral Research Associate Talks
 \, Shanlin Rao | Dalila Boi - Dr Shanlin RaoD\, Dr Dalila Boi\, Department
  of Pharmacology
DTSTART:20260306T130000Z
DTEND:20260306T140000Z
UID:TALK242113@talks.cam.ac.uk
CONTACT:116482
DESCRIPTION:Friday 6 March\, 13:00 - 14:00\n\nSpeakers: Postdoctoral Resea
 rch Associate Talks: Dr Shanlin Rao\, Dr Dalila Boi\n\nTalk Titles: \n\nDr
  Shanlin Rao: Cell-specific rewiring of GPCR signalling pathways: A system
 s pharmacology perspective\n\nDr Dalila Boi: Binding partners of Aurora ki
 nase A limit its accessibility to PROTAC-mediated degradation \n\nBiograph
 ies:\n\nDr Shanlin Rao: Shanlin received her undergraduate and doctoral tr
 aining in Biochemistry from the University of Oxford\, where she used mole
 cular modelling and simulations to examine hydrophobic gating in ion chann
 els within the groups of Professor Mark Sansom and Professor Stephen Tucke
 r. She then joined Professor Gerhard Hummer's group at the MPI of Biophysi
 cs in Frankfurt\, characterising membrane protein complexes in signalling 
 pathways that regulate autophagy and membrane repair. Her current research
  in the Marti-Solano lab applies computational analyses to integrate struc
 tural\, functional\, and omics data towards a systems-level understanding 
 of context-specific GPCR signalling.\n\nDr Dalila Boi: Dr Dalila Boi compl
 eted her academic training at Sapienza University of Rome in Italy\, and h
 as since worked on projects focusing on cancer cell biology\, protein–pr
 otein interactions\, and assay development for drug discovery. During her 
 Bachelor and Master Degrees in the laboratory of Prof Roberto Contestabile
  and Dr Angela Tramonti she worked on the in vitro purification and charac
 terisation of a protein complex essential for the tetrapyrroles biosynthes
 is in bacteria. Then she moved into the cancer cell biology field by joini
 ng the Dr Giulia Guarguaglini’ and Prof Alessandro Paiardini’s laborat
 ories\, where she completed her PhD in Life Sciences in 2022. Since then s
 he is involved in the research of novel pharmacological inhibitors of the 
 Aurora-A protein\, a mitotic kinase frequently over-expressed in cancer. I
 n 2024\, as part of a collaborative research project between the Italian N
 ational Research Council and the Department of Pharmacology at the Univers
 ity of Cambridge\, she was a visiting researcher in the laboratories of Pr
 of Laura Itzhaki and Dr Catherine Lindon. She is currently a postdoctoral 
 researcher in the laboratory of Dr Catherine Lindon\, where her research f
 ocuses on deciphering how the Aurora-A partners influence its degradabilit
 y through PROTACs in cells. Beyond the bench\, she is interested in scient
 ific writing\, and she is actively involved in outreach activities and sci
 ence communication for a non-academic audience. 
LOCATION:Seminar Room (Level 2)\, Dept of Pharmacology 
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