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SUMMARY:Pharmacology Seminar Series: Professor Meritxell Canals Buj\, Phar
 macology\, signalling and regulation of the mu-opioid receptor - Professor
  Meritxell Canals Buj
DTSTART:20260123T130000Z
DTEND:20260123T140000Z
UID:TALK242092@talks.cam.ac.uk
CONTACT:116482
DESCRIPTION:Friday 23 January\, 13:00 - 14:00\n\nSpeaker: Professor Meritx
 ell Canals Buj\n\nTalk Title: Pharmacology\, signalling and regulation of 
 the mu-opioid receptor\n\nBiography: Meritxell Canals joined the Universit
 y of Nottingham in October 2018 as a Professor of Cellular Pharmacology at
  the School of Life Sciences. Her research interests focus on understandin
 g the interactions between G Protein-Coupled Receptors (GPCRs) and intrace
 llular proteins\, and their consequences for receptor signalling and traff
 icking.\n\nMeritxell did her PhD in biochemistry at the University of Barc
 elona\, Spain and at Karolinska Institute in Sweden. Her PhD was part of a
  EU-funded multidisciplinary project that examined the interactions betwee
 n adenosine and dopamine receptors in Parkinson's Disease. During her PhD\
 , Meritxell obtained scholarships to visit the laboratories of Prof M Bouv
 ier (pioneer in the application of BRET to GPCRs\; Montreal\, Canada) and 
 Prof R Pepperkok (a leader in the development of FRET\; EMBL\, Germany). D
 r Canals completed postdoctoral training in a series of leading pharmacolo
 gy groups. In the laboratory of Prof G Milligan in Glasgow\, (2005-2008) s
 he focused on the functional consequences of GPCR co-expression and oligom
 erisation for which she developed novel RET techniques. As a senior post-d
 octoral fellow in the laboratory of Profs R Leurs and M Smit in Amsterdam 
 (2008-2010) she focused on the regulation\, pharmacology and medicinal che
 mistry of chemokine receptors. In 2010\, Meritxell was awarded a Monash Fe
 llowship to start her independent line of research within the Drug Discove
 ry Biology (DDB) Theme at the Monash Institute of Pharmaceutical Sciences 
 (MIPS). In 2017 she took a sabbatical year to work with her collaborators 
 in the departments of surgery (Prof N Bunnett) and pharmacology (Prof J Ja
 vitch) at Columbia University\, New York. At the end of 2018\, Meritxell m
 oved to the University of Nottingham\, to join the Centre of Membrane Prot
 ein and Receptors\, (COMPARE) a joined venture between the University of B
 irmingham and the University of Nottingham.
LOCATION:Seminar Room (Level 2)\, Dept of Pharmacology 
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