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SUMMARY:NK cell receptors: on with the old and in with the new - Professor
  Salim Khakoo\, Professor of Hepatology\, Southampton University
DTSTART:20260312T160000Z
DTEND:20260312T170000Z
UID:TALK242008@talks.cam.ac.uk
CONTACT:Liat Churley
DESCRIPTION:This Cambridge Immunology Network Seminar will take place on *
 Thursday 12 March 2026*\, starting at 4:00pm\, in the Ground Floor Lecture
  Theatre\, Jeffrey Cheah Biomedical Centre (JCBC)\n\n*Speaker:* Professor 
 Salim Khakoo\, Professor of Hepatology\, Southampton University\n\n*Title:
 * NK cell receptors: on with the old and in with the new\n\n*Abstract:* Na
 tural killer (NK) cells play a fundamental role in the immune response to 
 viruses and cancer.  As part of the innate immune system\, on an evolution
 ary scale\, they are considered to be relatively ancient.  However\, in ad
 dition to highly conserved receptors they also express a class of receptor
 s (the killer cell immunoglobulin-like receptors) that are rapidly evolvin
 g.  These receptors have MHC class I ligands and are associated with many 
 different diseases process.  They recognize peptides derived from both vir
 uses and cancer.  Interactions with viruses may have driven the selection 
 of KIR\, but recognition of cancer also provides a potential therapeutic o
 pportunity.\n\n*Host:* Professor Francesco Colucci\, School of Clinical Me
 dicine\, University of Cambridge\n\nRefreshments will be available followi
 ng the seminar.
LOCATION: Lecture Theatre\, Jeffrey Cheah Biomedical Centre\, Cambridge Bi
 omedical Campus
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