BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:*CANCELLED!* [NK cells in host immunity] - Dr Joseph Sun\, Cornell
 /Memorial Sloan Kettering Cancer Center
DTSTART:20260319T160000Z
DTEND:20260319T170000Z
UID:TALK240895@talks.cam.ac.uk
CONTACT:Liat Churley
DESCRIPTION:*Title:* NK cells in host immunity\n\n*Abstract:* Immunologica
 l memory is a hallmark feature of the mammalian adaptive immune response a
 nd essential for prolonged host control of pathogens. Although these featu
 res are attributed to T and B cells\, previous work has demonstrated that 
 natural killer (NK) cells\, which have traditionally been categorized as a
  component of innate immunity\, also possess the ability to undergo clonal
  proliferation and generate memory in response to pathogens. Here\, we see
 k to understand and dissect novel molecular pathways that underlie these 
 “adaptive” NK cell responses during cytomegalovirus infection. Our fin
 dings uncover a previously unrecognized\, host protective role for Wnt sig
 naling in NK cell-mediated antiviral immunity\, with implications for the 
 design of novel NK cell therapies.\n\n\n*Bio*: Joseph Sun received his PhD
  in immunology in 2005\, having trained with Mike Bevan in CD8+ T cell mem
 ory as a graduate student at the University of Washington. As a postdoc wi
 th Lewis Lanier at UCSF from 2006-2010\, he discovered that natural killer
  cells possess adaptive immune features including clonal expansion and lon
 g-lived memory following viral infection. He was recruited to Memorial Slo
 an Kettering Cancer Center in 2010 by Jim Allison\, and his lab has been i
 nterested in defining the underlying epigenetic\, transcriptional\, and me
 tabolic signals that govern innate and adaptive lymphocyte responses in ho
 st defense against pathogens and cancer.  \n\n*Hosts* Dr Tim Halim\, CRUK 
 & Dr Virginia Pedicord\, CITIID
LOCATION: Lecture Theatre\, Jeffrey Cheah Biomedical Centre\, Cambridge Bi
 omedical Campus
END:VEVENT
END:VCALENDAR