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CATEGORIES:Biochemistry Seminar Series - External Speakers
SUMMARY:Beak to Bedside - Understanding and controlling Ca
 mpylobacter - Andrew Grant - University of Cambrid
 ge
DTSTART;TZID=Europe/London:20251211T150000
DTEND;TZID=Europe/London:20251211T160000
UID:TALK235573AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/235573
DESCRIPTION:Dr Andrew Grant is an Associate Professor in Micro
 bial Pathogenesis in the Department of Veterinary 
 Medicine\, University of Cambridge. Andrew obtaine
 d his BSc degree in Biochemistry and Pharmacology 
 and a PhD in Molecular Microbiology at Southampton
  University and then moved to the University of Ca
 mbridge to a postdoctoral position. After a series
  of postdoctoral positions\, studying different en
 teric bacterial pathogens\, he moved into his curr
 ent position where his group uses genomic and func
 tional genomic approaches\, combined with molecula
 r\, proteomic and imaging techniques\, to determin
 e the basis by which bacterial pathogens survive i
 n different environments\, colonise their hosts an
 d cause disease. Andrew is also a HEI partner of Q
 uadram Institute Bioscience supporting the Institu
 tional Strategic Programme on Microbes in the Food
  Chain. Through the different research themes the 
 aim is to translate the findings into novel interv
 ention strategies\, including small-molecule thera
 peutics\, antibodies\, antimicrobial peptides and 
 vaccines.\n\nCampylobacter is the most common bact
 erial cause of human gastroenteritis in the world.
  An acute infection can have serious long-term con
 sequences\, including Guillain-Barré syndrome\, re
 active arthritis and irritable bowel syndrome. Cam
 pylobacter is commonly found in the gastrointestin
 al tracts of animals destined for human consumptio
 n\, with faecal contamination of meat\, especially
  chicken\, during processing a route of transmissi
 on to humans. In the UK\, Campylobacter infections
  are estimated to affect 1% of the population and 
 cost the economy ~£1 billion each year. The abilit
 y of Campylobacter to colonise and survive in many
  animal species and habitats makes them extremely 
 difficult to control\, and infection in humans rem
 ains difficult to prevent. There are no vaccines f
 or animals or humans. Worldwide there has been a r
 apid increase in antimicrobial resistant Campyloba
 cter strains\, making them a serious and growing p
 ublic health threat. There is a need to understand
  how Campylobacter survives in different environme
 nts\, colonises chickens (and other animals) and c
 auses disease in humans\, and to use this knowledg
 e to develop intervention strategies.\n\nIn the ta
 lk “Beak to Bedside – Understanding and controllin
 g Campylobacter”\, Andrew’s presentation will cove
 r recent and ongoing studies by his group focused 
 on different aspects of Campylobacter growth\, sur
 vival and intervention.\n
LOCATION:Jean Thomas Lecture theatre\, Sanger Building\, Te
 nnis Court Road
CONTACT:
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