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CATEGORIES:Isaac Newton Institute Seminar Series
SUMMARY:Using Data-driven Methods to Understand and Contro
 l Active Materials - Michael Hagan (Brandeis Unive
 rsity)
DTSTART;TZID=Europe/London:20250910T143000
DTEND;TZID=Europe/London:20250910T151000
UID:TALK233293AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/233293
DESCRIPTION:Active matter is composed of particles that genera
 te forces or motion\, which leads to spectacular e
 mergent dynamics. In principle\, active matter cou
 ld form the basis for a new class of materials wit
 h lifelike properties of biological organisms. Yet
 \, active materials exhibit diverse dynamical stat
 es\, most of which have chaotic dynamics that do n
 ot produce work or other useful functions. Thus\, 
 a robust control strategy is needed to drive activ
 e materials into an emergent state that correspond
 s to a desirable function. However\, designing con
 trol protocols requires accurate dynamical models\
 , which are not available for most active matter s
 ystems. Developing quantitative models using tradi
 tional statistical physics approaches is challengi
 ng because active materials lack the scale separat
 ion characteristic of equilibrium systems.&nbsp\;I
 n this presentation\, I will discuss efforts to co
 mbine machine learning\, other data-driven techniq
 ues\, and &nbsp\;physics-based models with control
  theory to address this challenge in the context o
 f a widely-used active material\, microtubule-base
 d active nematics. Recent advances in optogenetic 
 motors have enabled constructing the light-activat
 ed active nematics\, in which the activity can be 
 spatiotemporally controlled by shining light on th
 e sample. The challenge is to determine the spatio
 temporal light sequence required to drive the syst
 em into a desired behavior.I will describe two com
 plementary approaches to computationally determine
  an optimal light sequence. In the first\, we have
  adapted a method to discover optimal physics-base
 d continuum models directly from spatiotemporal da
 ta\, using sparse regression. We have identified s
 everal approaches to mitigate measurement errors i
 n the data. We find that the method can reveal the
  relative contributions of different physical mech
 anisms\, and quantitatively estimates key experime
 ntal parameters. Then\, we have developed a framew
 ork to combine the optimal physics-based model wit
 h optimal control theory to solve for the spatiote
 mporal activity profile that drives the system int
 o a desired state. We demonstrate that active mate
 rials can be driven into arbitrary behaviors\, inc
 luding those which do not correspond to dynamical 
 attractors and thus cannot be accessed without con
 trol.Since no model is perfectly accurate for a sp
 ecific system\, in the second approach we develop 
 a deep reinforcement learning (DRL) based controll
 er to enable model-free control of active material
 s. The controller discovers and implements spatiot
 emporal sequences of activity to drive a 2D active
  nematic system toward a prescribed dynamical stea
 dy-state. This framework does not require a detail
 ed physics model\, making it ideal for complex act
 ive materials that lack quantitative theoretical d
 escriptions. Furthermore\, the approach is extreme
 ly robust to noise and experimental measurement er
 ror. We compare the performance of the physics-bas
 ed and DRL-based controllers for active nematics.T
 his work was supported by DE-SC0022291. Preliminar
 y work was supported by NSF DMR-1855914 and DMR-20
 11846. Computing resources were provided by XSEDE 
 TG-MCB090163 and the Brandeis HPCC (DMR-MRSEC 2011
 846 and OAC-1920147).
LOCATION:External
CONTACT:
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