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SUMMARY:Pharmacology Postdoctoral Researcher Talks - Speaker to be confirm
 ed
DTSTART:20250228T160000Z
DTEND:20250228T170000Z
UID:TALK226870@talks.cam.ac.uk
CONTACT:124030
DESCRIPTION:Dr Lay Ping Ong\n\n\nTalk title: Cellular therapy for the fail
 ing heart - benefits of multicellularity?\n\n\nBiography:\n\nChronic heart
  failure is a clinically unmet need. Stem cells are cells that can turn in
 to any cell type in the body\, and so adding new heart muscle using a stem
  cell-based approach holds great promise to reinstate the pumping ability 
 of the heart.\n\n\nDr. Lay Ping Ong is a clinical academic (Internal Medic
 ine/Cardiology\, Cambridge) interested in advanced heart failure and heart
  transplantation. Her prior experience as a UK cardiothoracic surgical res
 ident led to her PhD in cardiac regeneration. During her PhD\, Dr. Ong dis
 covered that human embryonic stem cells (hESCs)-derived cardiomyocytes car
 ry a huge potential as a cellular therapy to cure heart failure. Then\, sh
 e pivoted into physician-scientist training to advance this work toward cl
 inics.\n\n\nCurrently\, Dr. Ong is funded by a joint MRC-Astra Zeneca fell
 owship\, which uses a combinatorial approach to data-driven target discove
 ry with downstream validation in complex human heart 3D assays. The ultima
 te aim is to develop novel therapies (stem cell-based and/or gene therapy)
  to treat chronic heart failure in collaboration with academics\, clinicia
 ns\, and industry scientists.\n\n\nDr Federico Bosetto\n\n\n\nTalk title: 
 Aptamers as therapeutic tools against resistant bacteria\n\n\nBiography:\n
 \n\nFederico Bosetto graduated in Biological Sciences and in Molecular and
  Cellular Biology\, both at the University of Bologna\, Bologna (Italy). I
 n 2021\, he got his PhD degree in Agricultural Science and Biotechnology a
 t the University of Udine\, Udine(Italy)\, submitting a PhD thesis on “D
 evelopment of synthetic methods\, namely oligonucleotide aptamers\, in ord
 er to stimulate the plant defense response in Arabidopsis thaliana”. In 
 2020\, he performed a PhD visiting period at Istitut Pasteur of Paris (Fra
 nce) at Bioorganic chemistry of nucleic acids group. After the PhD\, in 20
 21\, he joint Pure Biologics (Wrocław\, Poland) as R&D Scientist at Aptam
 ers group\, working on the development of chemically modified DNA aptamers
  for therapeutic purposes for human diseases. In 2023\, he joint the Unive
 rsity of Cambridge as Research Associate in Mela lab\, working on the deve
 lopment of DNA aptamers in the field of the antibiotic resistance.
LOCATION:Seminar Room (Level 2)\, Dept of Pharmacology 
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