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DTSTART:19700329T010000
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CATEGORIES:Fluid Mechanics (DAMTP)
SUMMARY:Evaporation dynamics of respiratory-like droplets 
 and their implications on virus infectivity - Javi
 er Rodríguez Rodríguez\, Carlos III University of 
 Madrid
DTSTART;TZID=Europe/London:20240701T133000
DTEND;TZID=Europe/London:20240701T143000
UID:TALK218278AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/218278
DESCRIPTION:Viruses can remain infective in the aerosolized so
 lid residue left upon the evaporation of respirato
 ry droplets for very long times. However\, the pre
 cise mechanisms that allow viral particles to endu
 re the harsh physico-chemical conditions found in 
 these drops for so long are poorly understood. In 
 this talk we present our ongoing theoretical and e
 xperimental study of the transport of solutes and 
 viral particles inside evaporating complex drops\,
  with the aim at elucidating the precise physico-c
 hemical mechanisms that ultimately lead to viral i
 nactivation. In a first part of the talk we presen
 t a model of the evaporation of complex drops\, co
 ntaining water\, salt\, and a glycoprotein (Mucin)
 . This model has been validated against experiment
 s of evaporating spherical droplets semi-levitated
  on superhydrophobic substrates\, as well as sessi
 le ones. This model is then used to estimate the v
 iral decay rate depending on the drop properties a
 nd atmospheric conditions. In a second part of the
  talk\, we develop a more comprehensive model of t
 he transport of salt and protein inside the drop. 
 We use this model to explain the spatial distribut
 ion of viral particles in the dry residue of a ses
 sile drop that we have observed experimentally. We
  conclude with a discussion of the plausible mecha
 nisms of viral inactivation\, based on our experim
 ents.
LOCATION:MR13
CONTACT:Professor Grae Worster
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