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SUMMARY:Maturing the heart: implications for disease modelling\, drug disc
 overy & regenerative medicine - Prof Enzo Porrello - Murdoch Children's Re
 search Institute\, Australia
DTSTART:20240411T120000Z
DTEND:20240411T130000Z
UID:TALK209857@talks.cam.ac.uk
CONTACT:Denise Hatherly
DESCRIPTION:Human pluripotent stem cell (PSC)-derived cardiomyocytes are e
 merging as a powerful platform for cardiovascular drug discovery and regen
 erative medicine. However\, PSC-derived cardiomyocytes are typically immat
 ure\, which limits their capacity to predict human biology and disease mec
 hanisms. Here\, I will discuss recent research from our laboratory definin
 g mechanisms controlling cardiomyocyte maturation during postnatal develop
 ment with implications for cardiac disease modelling\, drug discovery and 
 regenerative medicine.
LOCATION: Heart and Lung Institute\, Cambridge Biomedical Campus
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