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SUMMARY:Single Cell 3D Genome Reconstruction in the Haploid Setting Using 
 Rigidity Theory - Kaie Kubjas (Aalto University)
DTSTART:20240125T141500Z
DTEND:20240125T151500Z
UID:TALK208081@talks.cam.ac.uk
DESCRIPTION:We study the problem of 3D genome reconstruction from contact 
 count matrices for single cell data\, and the uniqueness of such reconstru
 ctions in the setting of haploid organisms. We consider multiple models as
  representations of this problem\, and use techniques from graph rigidity 
 theory to determine uniqueness. Finally\, we compare the 3D reconstruction
 s for different models using semidefinite programming. The talk is based o
 n joint work with Sean Dewar\, Georg Grasegger\, Fatemeh Mohammadi and Ant
 hony Nixon.
LOCATION:Seminar Room 1\, Newton Institute
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