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CATEGORIES:Parasitology Seminars
SUMMARY:Investigating host-parasite interactions in malari
 a to improve diagnostics and treatments - Prof Aub
 rey Cunnington - Imperial College London
DTSTART;TZID=Europe/London:20231206T140000
DTEND;TZID=Europe/London:20231206T150000
UID:TALK207316AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/207316
DESCRIPTION:Severe malaria has a mortality rate of 10-20% desp
 ite antimalarial treatment\, resulting in about 60
 0\,000 deaths every year\, mostly children in sub-
 Saharan Africa. Despite extensive research on trea
 tments to reduce this mortality rate\, there are n
 o proven effective treatments which can be added t
 o antimalarials to save lives. One reason for this
  may be an over-simplified view of the pathogenesi
 s of severe malaria. A second reason may be a lack
  of specificity in the diagnosis of severe malaria
  – with many cases actually having an alternative 
 or additional cause of their life-threatening illn
 ess. Aubrey Cunnington’s group have used transcrip
 tomics to understand the host-parasite interaction
 s driving malaria pathogenesis\, to identify trans
 lationally-relevant model systems for pre-clinical
  testing of adjunctive treatments\, and as a novel
  approach to diagnosis. In this seminar Aubrey wil
 l outline key findings from these studies and will
  explain how they are being translated into the ne
 xt generation of diagnostic and prognostic tests f
 or malaria.
LOCATION:Seminar Room\, Tennis Court Road\, Dept of Patholo
 gy.
CONTACT:Anna Protasio
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