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SUMMARY:GABA-A receptor subtypes controlling pain and itch - Professor Han
 ns Ulrich Zeilhofer\, Department of Chemistry and Applied Bioscience\, ETH
  Zürich
DTSTART:20231103T123000Z
DTEND:20231103T133000Z
UID:TALK206341@talks.cam.ac.uk
CONTACT:116482
DESCRIPTION:Biography\n\nHanns Ulrich Zeilhofer is Professor of Pharmacolo
 gy at the University of Zurich (UZH) and the Swiss Federal Institute of Te
 chnology (ETH) Zurich. He is an MD by training and holds a board certifica
 tion in Clinical Pharmacology. He did his postdoctoral training at the Uni
 versity of Erlangen\, the Max-Planck Institute of Biophysical Chemistry an
 d at ETH Zürich\, before he joined UZH as professor of pharmacology. He h
 as served as the director of the Institute of Pharmacology and Toxicology 
 of the University of Zurich for 16 years and as a member of the research c
 ouncil of the Swiss National Science Foundation for 8 years. He is also a 
 founding member of the Drug Discovery network Zurich (DDNZ). Currently\, h
 e serves as deputy dean of the Faculty of Medicine at UZH.\n\nHis research
  has been supported by grants from the European Research Council (ERC)\, t
 he Swiss National Science Foundation and the Wellcome Trust\, among others
 . Current research projects concentrate on the cellular and molecular basi
 s of nociceptive processing in the spinal dorsal horn. Central to his grou
 p’s research is the control of nociception by dorsal horn inhibitory neu
 rotransmitters and inhibitory interneurons\, which he and his team study o
 n the molecular\, cellular and circuit level.\n\nMolecular aspects include
  strategies to restore proper synaptic inhibition in pathological pain sta
 tes. These projects have led to the identification a2 GABAA and a3 glycine
  receptors as potential targets in chronic pain conditions. To address the
  diversity of inhibitory dorsal horn neurons and their integration into lo
 cal circuits and long-range projections his team has established a highly 
 versatile toolbox of transgenic mouse lines and viruses suitable for condi
 tional ablation\, silencing and activation of genetically defined dorsal h
 orn interneuron populations.\n\nZoom link: https://zoom.us/j/98809937536?p
 wd=T3BpN0E2UUwvV1ROejdodFVhYVpqdz09\n\nMeeting ID: 988 0993 7536\n\nPassco
 de: 4PcSP9DECJ
LOCATION:Seminar Room (Level 2)\, Dept of Pharmacology 
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