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SUMMARY:Active biomolecular condensates on membranes - Christoph Weber (Un
 iversität Augsburg)
DTSTART:20231009T105000Z
DTEND:20231009T113000Z
UID:TALK204769@talks.cam.ac.uk
DESCRIPTION:The physics of biomolecular condensates provides a plethora of
  functionalities to living cells\, including fluctuation buffering\, selec
 tion and regulation of chemical reactions\, and switch-like transitions of
  the condensate composition. In the presence of membrane surfaces\, biomol
 ecular condensates exhibit an even richer functionality by exploiting surf
 ace phase transitions\, including wetting\, prewetting\, and surface phase
  separation. In contrast to the wetting of water drops on plant leaves\, c
 ellular surfaces are membranes with rich physico-chemical properties that 
 include the active binding of condensate molecules into the membrane. Usin
 g theory\, we show that active membrane binding and the physics of phase s
 eparation significantly alter the kinetics of wetting\, leading to non-equ
 ilibrium steady states with condensate shapes reminiscent of a fried egg o
 r a mushroom.&nbsp\;
LOCATION:Seminar Room 1\, Newton Institute
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