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CATEGORIES:Isaac Newton Institute Seminar Series
SUMMARY:Mechanical behaviors of collective cell assemblies
  during migration and extrusion. - Benoit Ladoux (
 Institut Jacques Monod)
DTSTART;TZID=Europe/London:20230706T090000
DTEND;TZID=Europe/London:20230706T100000
UID:TALK201148AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/201148
DESCRIPTION:Epithelia are communities of epithelial cells with
  close intercellular communications and of highly 
 ordered coordination in their motility. Tissues ca
 n adjust their internal contractile stresses and o
 rganization in response to different stimuli\, lea
 ding to distinct dynamics. Mechanical&nbsp\;proper
 ties of epithelial tissues are important for our u
 nderstanding in many vital biological processes\, 
 including homeostasis\, morphogenesis\, and metast
 asis and are tightly regulated by cell-cell intera
 ctions. I will present examples highlighting the i
 mportance of collective behaviours to understand t
 issue regulation. In the first part\, I will focus
  on collective cell migration and the emergence of
  cell polarity. In the second part\, i will talk a
 bout cell extrusion form epithelial tissues and ho
 w mechanics can regulate the fate of extruding cel
 ls. 
LOCATION:Seminar Room 1\, Newton Institute
CONTACT:
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