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SUMMARY:Microglial states and nomenclature - Prof. Amanda Sierra. Achucarr
 o Basque Centre for Neuroscience\, Spain
DTSTART:20221107T160000Z
DTEND:20221107T170000Z
UID:TALK183713@talks.cam.ac.uk
CONTACT:Timothy Birkle
DESCRIPTION:Microglial research has advanced considerably in recent decade
 s yet has been constrained by a rolling series of dichotomies such as “r
 esting versus activated” and “M1 versus M2”. This dualistic classifi
 cation of good or bad microglia is inconsistent with the wide repertoire o
 f microglial states and functions in development\, plasticity\, aging and 
 diseases that were elucidated in recent years. New designations continuous
 ly arising in an attempt to describe the different microglial states\, not
 ably defined using transcriptomics and proteomics\, may easily lead to a m
 isleading\, although unintentional\, coupling of categories and functions.
  To address these issues\, we assembled a group of multidisciplinary exper
 ts to discuss our current understanding of microglial states as a dynamic 
 concept and the importance of addressing microglial function. Here\, we pr
 ovide a conceptual framework and recommendations on the use of microglial 
 nomenclature for researchers\, reviewers\, and editors\, which will serve 
 as the foundations for a future white paper
LOCATION:Zoom: https://zoom.us/j/94128601767?pwd=UklLN2h5ZGNVL3BMYVNqdXh3d
 jRXZz09 (Meeting ID: 941 2860 1767\, Passcode: E2Gpvk35FP)
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