BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:News from the RNA World - Peter Stadler\,  Universität Leipzig
DTSTART:20090415T110000Z
DTEND:20090415T120000Z
UID:TALK17914@talks.cam.ac.uk
CONTACT:Ana Mosterin
DESCRIPTION:In contrast to the fairly reliable and complete annotation of 
 protein-coding genes in the human genome\, comprehensive information for n
 on-coding RNAs is still lacking. Both quality and coverage of ncRNA annota
 tion is not comparable to that of protein coding genes. In\nthis presentat
 ion I will focus on the bioinformatics aspects of this "modern RNA world".
  In particular\, approaches towards annotating the plethora on ncRNAs and 
 ncRNA candidates\, and first studies into the\nevolution of these transcri
 pts at genome wide scale will be discussed. RNA gene finding is a difficul
 t task. While RNAs with evolutionary conserved secondary structure can be 
 found by a combination of structure prediction and comparative genomics\, 
 little is known for unstructured RNAs. The conservation of transcript stru
 ctures\, however\, provides a promising starting point. Complementary to g
 ene finding\, the recognition of members of known classes and the classifi
 cation of\nnovel transcripts posed important computational problems. We wi
 ll briefly touch upon these topics in the context of microRNAs and snoRNAs
 \, and discuss efficient structural clustering approaches.
LOCATION:Basement Seminar Room\, Department of Zoology
END:VEVENT
END:VCALENDAR