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CATEGORIES:Babraham Seminar
SUMMARY:BYOB – Organising Appropriate Gatherings in the Ly
 mph Node - Dr Ed Roberts\; CRUK Beatson Institute
DTSTART;TZID=Europe/London:20220930T130000
DTEND;TZID=Europe/London:20220930T140000
UID:TALK176486AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/176486
DESCRIPTION:The immune system faces an information transfer pr
 oblem in appropriately directing T-cell responses 
 in the lymph node\; a site distal to immune challe
 nges. Contextual information relevant to antigens 
 must be encoded and transmitted to T-cells to allo
 w diverse responses to occur within the same lymph
  node ensuring both robust immune response generat
 ion alongside maintenance of tolerance. The comple
 xity of this problem becomes particularly apparent
  when the diversity of the cell types involved in 
 directing T-cell responses are considered with man
 y residing within the lymph node and never directl
 y encountering antigens within their tissue contex
 t. Using models of both infection and cancer devel
 opment we have investigated how tissues communicat
 e with the lymph node to solve this conundrum.\n\n
 Click here to join live - https://us06web.zoom.us/
 j/84993693848 
LOCATION:Online via zoom &amp\; Kings Hedges Room 
CONTACT:Bobbie Claxton
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